ISAVRAD Research Cores

Learn more about each Research Cores that makes ISAVRAD run smoothly.

Administrative Core

The Administrative Core (AC) provides essential support and coordination to the other Cores and Projects of the ISAVRAD.

Neuroimaging Core

The Neuroimaging Core manages neuroimaging acquisition (2 assessments/subject), quality control, harmonization, data archiving and data sharing at all study sites. Image acquisition, quality control and harmonization strategies emulate those of ADNI3 and Mark VCID supplemented by team expertise.

Data Management and Statistics Core

The Data Management and Statistics Core (DM&SC) is one of 4 Cores supporting the scientific research activities of the ISAVRAD Program Projects and is responsible for management, reporting and sharing of raw and meta-data generated.

Clinical Core

Will enroll and conduct in-depth clinical evaluations of 4,300 older adults with (75% of the sample) and without (25% of the sample) exposure to SARS-CoV-2 within the first two years of the pandemic.

Biomarker Core

The Biomarker Core (BMC) will receive buffy coat, plasma, and PAXgene RNA from all participating sites. We will process blood samples and store DNA, RNA and plasma.

The ISAVRAD Consortium explores how COVID-19 and genetics affect brain health, focusing on diverse communities worldwide.

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